Find a trial
For several compounds in the register, a clinical trial is the only lawful way to receive them in the UK. This site says that on every one of those records, then leaves people to work out how. This is the how.
Why this is links rather than a list. Recruitment opens and closes constantly, and a hand-maintained list of open trials would be out of date within weeks. A stale list is worse than none, because it sends people to closed studies and looks authoritative doing it. So the table below points at the official registries with the right search terms already in, and those stay current without anyone maintaining them.
01Search by compound
Every compound here has no UK marketing authorisation. For these, a trial is the lawful alternative to the grey market rather than a second-best option.
| Compound | Trial programme | Being studied for | Search |
|---|---|---|---|
| Retatrutide | TRIUMPH | Obesity and type 2 diabetes | UK Global |
| CagriSema | REDEFINE | Obesity and type 2 diabetes | UK Global |
| Cagrilintide | REDEFINE | Obesity | UK Global |
| Survodutide | SYNCHRONIZE, LIVERAGE | Obesity, and liver disease including cirrhosis | UK Global |
| Orforglipron | ATTAIN, ACHIEVE | Obesity and type 2 diabetes | UK Global |
| Mazdutide | GLORY, DREAMS | Obesity and type 2 diabetes | UK Global |
| SS-31 | Elamipretide programme | Rare mitochondrial conditions | UK Global |
| Tesamorelin | Various | HIV-associated lipodystrophy | UK Global |
The UK link searches Be Part of Research, the NIHR's free UK-wide service. The global link searches ClinicalTrials.gov filtered to recruiting studies, which is useful for seeing whether a programme exists at all even when nothing is open here.
02The two places worth searching
Start here
Be Part of Research
The NIHR's service, free, covering England, Scotland, Wales and Northern Ireland. Search by condition and location, or register your interest and be matched. Also available through the NHS App. You need to be 18 or over and living in the UK.
For the full picture
ClinicalTrials.gov
The international registry. More technical, and the place to see a whole programme including studies not running here. Useful for working out how far along a compound actually is, rather than how far along a vendor says it is.
03What taking part actually involves
Worth knowing before you enquire, because a lot of people picture something closer to a private clinic than what it is.
- It is free, and travel costs are often reimbursed. You are not buying anything.
- You might get placebo. In most of these trials there is a control arm, and you will not know which you are in. That is the point of the design and it is the honest catch.
- You will be monitored properly. Bloods, observations, a clinical team who know what you are taking. That is the single biggest difference from buying online.
- You can leave whenever you want, without giving a reason, and it does not affect your NHS care.
- Most people who enquire do not qualify. Entry criteria are strict, often on BMI, existing conditions and other medicines. Being turned down is normal and not personal.
- There is real paperwork, a consent process, and time commitment. Visits can be frequent.
04Who authorises this, and why that matters
A clinical trial of a medicine in the UK cannot begin until the MHRA has reviewed and authorised it, and the MHRA inspects trial sites. Research ethics committees, overseen by the Health Research Authority, review whether the study is acceptable to run at all.
A trial means a regulator has assessed the protocol, an ethics committee has approved it, the product is manufactured to standard, a named clinician is responsible for you, and results get published.
An unlicensed vial from an online seller has none of those. Same compound, entirely different situation, and the difference is not paperwork. It is whether anyone is accountable if something goes wrong.
05How to actually enquire
- Search the registry using the links above, or by condition rather than compound, since trials are listed by what they treat.
- Check the location. Many run from a handful of sites and travel may be substantial.
- Read the eligibility criteria before contacting anyone. It saves everybody time.
- Contact the study team directly using the details on the listing. You do not need a referral to enquire.
- Tell your GP either way. They may know of studies, and they need to know what you are taking if you are accepted.
You can also simply ask your GP or specialist whether they know of anything relevant. Health professionals can use Be Part of Research to signpost patients, and some practices are research-active themselves.
06What this is not
- Not an endorsement of any trial or compound. A trial existing means a question is being asked, not that the answer is known.
- Not a route to getting a drug you have decided you want. You may be given placebo, and you may not qualify.
- Not a substitute for licensed treatment. If something licensed would help you now, that is worth pursuing rather than waiting.
- Not maintained as a list of open studies. The registries do that, and they do it better.